When you design a Power Point presentation for audiences that may have persons with low vision, put yourself in their shoes by imagining you are viewing the presentation through a shower curtain. What will you need to be able to actually see the presentation?
San Serif fonts should always be used for text and headings of more than one line.
Sans serif fonts are made up of mainly straight lines. Sans serif fonts are easier to read in continuous text. On the other hand, serif fonts have short strokes that project from the ends of the main stroke that make up a character. Although serif typefaces often work well in headings and personal stationery, they can be difficult to read in continuous text.