Glaucoma
Glaucoma causes damage to the optic nerve. Most commonly, this occurs due to increasing internal pressure in the eye because of problems with the flow or drainage of fluid within the eye. It can also occur when the internal pressure of the eye does not increase (normal tension glaucoma), but there is not enough blood flow to the optic nerve. There are no early symptoms in the most common form of glaucoma, but the first signs of damage are defects in side (peripheral) vision and difficulty with night vision. If diagnosed early, it can be treated with drugs, or sometimes surgery can minimize vision loss.
Images credit: National Eye Institute, NIH